Susceptibility of Mastomys natalensis to Brugia malayi following pretreatment with antifilarials.
Identifieur interne : 00D972 ( Main/Exploration ); précédent : 00D971; suivant : 00D973Susceptibility of Mastomys natalensis to Brugia malayi following pretreatment with antifilarials.
Auteurs : K. Tyagi [Inde] ; P K Murthy ; A B SenSource :
- Folia parasitologica [ 0015-5683 ] ; 1990.
Descripteurs français
- KwdFr :
- Animaux, Brugia (croissance et développement), Brugia (immunologie), Diéthylcarbamazine (pharmacologie), Diéthylcarbamazine (usage thérapeutique), Femelle, Filaricides (pharmacologie), Filaricides (usage thérapeutique), Filariose lymphatique (), Filariose lymphatique (immunologie), Filariose lymphatique (parasitologie), Lévamisole (pharmacologie), Lévamisole (usage thérapeutique), Muridae, Mâle, Pipérazines (pharmacologie), Pipérazines (usage thérapeutique), Susceptibilité à une maladie.
- MESH :
- croissance et développement : Brugia.
- immunologie : Brugia, Filariose lymphatique.
- parasitologie : Filariose lymphatique.
- pharmacologie : Diéthylcarbamazine, Filaricides, Lévamisole, Pipérazines.
- usage thérapeutique : Diéthylcarbamazine, Filaricides, Lévamisole, Pipérazines.
- Animaux, Femelle, Filariose lymphatique, Muridae, Mâle, Susceptibilité à une maladie.
English descriptors
- KwdEn :
- Animals, Brugia (growth & development), Brugia (immunology), Diethylcarbamazine (pharmacology), Diethylcarbamazine (therapeutic use), Disease Susceptibility, Elephantiasis, Filarial (immunology), Elephantiasis, Filarial (parasitology), Elephantiasis, Filarial (prevention & control), Female, Filaricides (pharmacology), Filaricides (therapeutic use), Levamisole (pharmacology), Levamisole (therapeutic use), Male, Muridae, Piperazines (pharmacology), Piperazines (therapeutic use).
- MESH :
- chemical , pharmacology : Diethylcarbamazine, Filaricides, Levamisole, Piperazines.
- growth & development : Brugia.
- immunology : Brugia, Elephantiasis, Filarial.
- parasitology : Elephantiasis, Filarial.
- prevention & control : Elephantiasis, Filarial.
- chemical , therapeutic use : Diethylcarbamazine, Filaricides, Levamisole, Piperazines.
- Animals, Disease Susceptibility, Female, Male, Muridae.
Abstract
Mastomys natalensis pretreated with diethylcarbamazine (DEC), levamisole or centperazine were exposed to the standard inoculum of infective larvae of Brugia malayi. Percentage 'take' of infection, duration of prepatent period, course of microfilaraemia and number of adult worms recovered were compared with those of untreated infected Mastomys (control). DEC and centperazine did not alter the 'take' (DEC/centperazine: 100%; control: 88.24%) and the average prepatent period (DEC: 105.44 days; centperazine: 105.18 days, control: 109.20 days). In levamisole pretreated animals on the other hand, the 'take' was much lower (68.18%) with extended prepatent period (125.87 days). However, unlike centperazine and control, the course of microfilaraemia was identical in DEC and levamisole pretreated animals. The average adult worm recovery was significantly high in centperazine pretreated animals being 14.09 as against 8.12, 7.46 and 8.42 in DEC, levamisole pretreated and control animals, respectively.
PubMed: 2227711
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 005E64
- to stream PubMed, to step Curation: 005E64
- to stream PubMed, to step Checkpoint: 005E64
- to stream Ncbi, to step Merge: 004A13
- to stream Ncbi, to step Curation: 004A13
- to stream Ncbi, to step Checkpoint: 004A13
- to stream Main, to step Merge: 00E548
- to stream Main, to step Curation: 00D972
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Susceptibility of Mastomys natalensis to Brugia malayi following pretreatment with antifilarials.</title><author><name sortKey="Tyagi, K" sort="Tyagi, K" uniqKey="Tyagi K" first="K" last="Tyagi">K. Tyagi</name><affiliation wicri:level="1"><nlm:affiliation>Division of Parasitology, Central Drug Research Institute, Lucknow, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Division of Parasitology, Central Drug Research Institute, Lucknow</wicri:regionArea><wicri:noRegion>Lucknow</wicri:noRegion></affiliation></author><author><name sortKey="Murthy, P K" sort="Murthy, P K" uniqKey="Murthy P" first="P K" last="Murthy">P K Murthy</name></author><author><name sortKey="Sen, A B" sort="Sen, A B" uniqKey="Sen A" first="A B" last="Sen">A B Sen</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1990">1990</date><idno type="RBID">pubmed:2227711</idno><idno type="pmid">2227711</idno><idno type="wicri:Area/PubMed/Corpus">005E64</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">005E64</idno><idno type="wicri:Area/PubMed/Curation">005E64</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">005E64</idno><idno type="wicri:Area/PubMed/Checkpoint">005E64</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">005E64</idno><idno type="wicri:Area/Ncbi/Merge">004A13</idno><idno type="wicri:Area/Ncbi/Curation">004A13</idno><idno type="wicri:Area/Ncbi/Checkpoint">004A13</idno><idno type="wicri:doubleKey">0015-5683:1990:Tyagi K:susceptibility:of:mastomys</idno><idno type="wicri:Area/Main/Merge">00E548</idno><idno type="wicri:Area/Main/Curation">00D972</idno><idno type="wicri:Area/Main/Exploration">00D972</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Susceptibility of Mastomys natalensis to Brugia malayi following pretreatment with antifilarials.</title><author><name sortKey="Tyagi, K" sort="Tyagi, K" uniqKey="Tyagi K" first="K" last="Tyagi">K. Tyagi</name><affiliation wicri:level="1"><nlm:affiliation>Division of Parasitology, Central Drug Research Institute, Lucknow, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Division of Parasitology, Central Drug Research Institute, Lucknow</wicri:regionArea><wicri:noRegion>Lucknow</wicri:noRegion></affiliation></author><author><name sortKey="Murthy, P K" sort="Murthy, P K" uniqKey="Murthy P" first="P K" last="Murthy">P K Murthy</name></author><author><name sortKey="Sen, A B" sort="Sen, A B" uniqKey="Sen A" first="A B" last="Sen">A B Sen</name></author></analytic><series><title level="j">Folia parasitologica</title><idno type="ISSN">0015-5683</idno><imprint><date when="1990" type="published">1990</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Brugia (growth & development)</term><term>Brugia (immunology)</term><term>Diethylcarbamazine (pharmacology)</term><term>Diethylcarbamazine (therapeutic use)</term><term>Disease Susceptibility</term><term>Elephantiasis, Filarial (immunology)</term><term>Elephantiasis, Filarial (parasitology)</term><term>Elephantiasis, Filarial (prevention & control)</term><term>Female</term><term>Filaricides (pharmacology)</term><term>Filaricides (therapeutic use)</term><term>Levamisole (pharmacology)</term><term>Levamisole (therapeutic use)</term><term>Male</term><term>Muridae</term><term>Piperazines (pharmacology)</term><term>Piperazines (therapeutic use)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Brugia (croissance et développement)</term><term>Brugia (immunologie)</term><term>Diéthylcarbamazine (pharmacologie)</term><term>Diéthylcarbamazine (usage thérapeutique)</term><term>Femelle</term><term>Filaricides (pharmacologie)</term><term>Filaricides (usage thérapeutique)</term><term>Filariose lymphatique ()</term><term>Filariose lymphatique (immunologie)</term><term>Filariose lymphatique (parasitologie)</term><term>Lévamisole (pharmacologie)</term><term>Lévamisole (usage thérapeutique)</term><term>Muridae</term><term>Mâle</term><term>Pipérazines (pharmacologie)</term><term>Pipérazines (usage thérapeutique)</term><term>Susceptibilité à une maladie</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Diethylcarbamazine</term><term>Filaricides</term><term>Levamisole</term><term>Piperazines</term></keywords><keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Brugia</term></keywords><keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Brugia</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Brugia</term><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Brugia</term><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Diéthylcarbamazine</term><term>Filaricides</term><term>Lévamisole</term><term>Pipérazines</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Diethylcarbamazine</term><term>Filaricides</term><term>Levamisole</term><term>Piperazines</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Diéthylcarbamazine</term><term>Filaricides</term><term>Lévamisole</term><term>Pipérazines</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Disease Susceptibility</term><term>Female</term><term>Male</term><term>Muridae</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Femelle</term><term>Filariose lymphatique</term><term>Muridae</term><term>Mâle</term><term>Susceptibilité à une maladie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Mastomys natalensis pretreated with diethylcarbamazine (DEC), levamisole or centperazine were exposed to the standard inoculum of infective larvae of Brugia malayi. Percentage 'take' of infection, duration of prepatent period, course of microfilaraemia and number of adult worms recovered were compared with those of untreated infected Mastomys (control). DEC and centperazine did not alter the 'take' (DEC/centperazine: 100%; control: 88.24%) and the average prepatent period (DEC: 105.44 days; centperazine: 105.18 days, control: 109.20 days). In levamisole pretreated animals on the other hand, the 'take' was much lower (68.18%) with extended prepatent period (125.87 days). However, unlike centperazine and control, the course of microfilaraemia was identical in DEC and levamisole pretreated animals. The average adult worm recovery was significantly high in centperazine pretreated animals being 14.09 as against 8.12, 7.46 and 8.42 in DEC, levamisole pretreated and control animals, respectively.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Murthy, P K" sort="Murthy, P K" uniqKey="Murthy P" first="P K" last="Murthy">P K Murthy</name><name sortKey="Sen, A B" sort="Sen, A B" uniqKey="Sen A" first="A B" last="Sen">A B Sen</name></noCountry><country name="Inde"><noRegion><name sortKey="Tyagi, K" sort="Tyagi, K" uniqKey="Tyagi K" first="K" last="Tyagi">K. Tyagi</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00D972 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00D972 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:2227711
|texte= Susceptibility of Mastomys natalensis to Brugia malayi following pretreatment with antifilarials.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:2227711" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |